Analytical element containing photosensitive compound and...

Details Analytical element containing photosensitive compound and... Analytical element containing photosensitive compound and...

G - Physics

01

N

150/15

G01N 33/52 (2006.01) C12Q 1/00 (2006.01) C12Q 1/50 (2006.01)

Patent

CA 1278243

ANALYTICAL ELEMENT CONTAINING PHOTOSENSITIVE COMPOUND AND FILTER LAYER AND METHOD OF USE Abstract of the Disclosure A multilayer analytical element for the determination of a clinically significant enzyme analyte comprises a photosensitive compound (e.g. a photosensitive dye or dye precursor) and a filter layer containing one or more filter dyes. The filter layer is situated in the element such that incident radiation used to detect a density change resulting from interaction of the analyte and the photosensi- tive compound passes through the filter layer before it reaches the photosensitive compound. The use of the filter layer inhibits premature changes in the photosensitive compound caused by incident radia- tion. This element is particularly useful for the determination of creatine kinase or one of its iso- enzymes, e.g. creatine kinase-MB.

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