Analytical element having improved spreading zone and method...

C - Chemistry – Metallurgy – 12 – Q

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150/14, 150/3

C12Q 1/00 (2006.01) C12Q 1/48 (2006.01) G01N 33/50 (2006.01) G01N 33/52 (2006.01)

Patent

CA 1223510

-0- ANALYTICAL ELEMENT HAVING IMPROVED SPREADING ZONE AND METHOD OF USE Abstract of the Disclosure A dry element capable of use for the analysis or transport of liquids comprises an isotropically porous zone which comprises a blush polymer having dispersed wherein a particulate material and a nonpolymeric heterocyclic, aliphatic or carbocyclic quaternary ammonium compound comprising at least 12 carbon atoms therein. This compound is present in the porous zone in an amount of at least about 2 weight percent, based on the dry weight of the blush polymer. The porous zone of this element has improved cohesive strength which improves its resistance to abrasion. The element can be used to determine an analyte in an aqueous liquid, such as biological fluids.

454904

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