B - Operations – Transporting – 01 – D
Patent
B - Operations, Transporting
01
D
B01D 21/26 (2006.01) G01N 15/05 (2006.01) G01N 21/07 (2006.01) G01N 33/49 (2006.01) G01N 35/00 (2006.01)
Patent
CA 2082827
An analytical rotor (10), for sepa- rating cellular components from a bio- logical sample includes a plurality of in- ternal chambers and passages for com- bining the cell-free sample with one or more reagents and distributing the sam- ple to a plurality of individual test wells (92). The chambers and passages neces- sary for separating cellular components from a sample such as whole blood in- clude a measuring chamber (40), an overflow chamber (44), a separation chamber (60), and a reagent chamber (80), The measuring chamber (40) and overflow chamber (44) have capillary di- mensions. so that an initial volume of whole blood partitions therebetween, with the measuring chamber filling first to provide a preselected volume. The se- paration chamber (60) is located radially outward from both the measuring cham- ber (40) and the reagent chamber (80) so that spinning of the rotor causes both the reagent and the measured blood vo- lume to flow outward into the separation chamber (60). A collection chamber (90) is formed to receive the plasma from the separation chamber (60). Further spinning of rotor causes the plasma to flow radially outward into a plurality of test wells (92) formed around the periphery of the collec- tion chamber (90). Testing of the separated plasma volumes may be performed without removing the plasma from the rotor.
Braynin Boris
Burd Tammy L.
Ostoich Vladimir
Schembri Carol T.
Abaxis Inc.
Smart & Biggar
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