Analytical technique for oligonucleotide analogs

Details Analytical technique for oligonucleotide analogs Analytical technique for oligonucleotide analogs

B - Operations, Transporting

01

J

B01J 20/26 (2006.01) C07H 1/06 (2006.01) C07H 19/04 (2006.01) C07H 21/00 (2006.01) C12N 15/10 (2006.01) G01N 27/447 (2006.01)

Patent

CA 2149630

2149630 9414824 PCTABS00032 Disclosed is a substrate useful for separating unmodified and modified mononucleotides and oligonucleotides. The substrate includes at least 12 % polymer in at least 50 % (volume:volume) organic solvent, the organic solvent being a denaturing agent. This substrate is easily removable from the capillary using low pressure. Also provided is a method of separating unmodified and modified mononucleotides and oligonucleotides utilizing this substrate.

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