C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
150/3.1
C12Q 1/28 (2006.01) G01N 33/50 (2006.01) G01N 33/72 (2006.01)
Patent
CA 1209887
ABSTRACT OF THE DISCLOSURE A test composition, device and method for deter- mining a peroxidatively active substance in a test sample, as well as a method for preparing the device, are disclosed. The composition comprises an organic hydroperoxide and an indicator capable of providing a detectable response in the presence of the organic hydroperoxide and peroxidatively active substance, wherein the organic hydroperoxide is a substituted cumene hydroperoxide having the formula: Image in which any one of the X substituents is lower alkyl of from 1 to 6 carbon atoms, C1, Br, I, NO2 or carboxyl; or any two of the X substituents, same or different, are lower alkyl of from 1 to 6 carbon atoms, C1, Br, I, NO2 or carboxyl. The device com- prises a carrier matrix incorporated with the com- position, and the method comprises contacting a test sample with the device and observing a detectable response in the device. A method for preparing the device comprises preparing a solution of the com- position, wetting the carrier matrix therewith and drying the wetted matrix.
442761
Miles Laboratories Inc.
Osler Hoskin & Harcourt Llp
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