Analytical tracers for cancer, particularly malignant breast...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/57 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C12N 9/64 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2073860

A gene is provided which codes for a new member of the metalloproteinase family which has been discovered to be specifically linked to invasive breast cancer. Also provided are methods for diagnosing said cancer by detecting the tracer or its nucleotide sequence, and treatment or prevention by inhibiting or modifying the activity or binding of the tracer, or disrupting its synthesis.

2073860 9209701 PCTABS00130 La présente invention porte sur un gène codant pour un nouvel élément de la famille des métalloprotéinases qui a été découvert comme étant spécifiquement associé au cancer du sein invasif, ainsi que sur des procédés de diagnostic pour un tel cancer comprenant la détection du marqueur ou de sa séquence nucléotidique, et sur le traitement ou la prophylaxie par inhibition, modification de l'activité ou liaison du marqueur, ou par perturbation de sa synthèse.

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