Analyzing histamine h4 receptor-mediated effects in whole blood

Details Analyzing histamine h4 receptor-mediated effects in whole blood Analyzing histamine h4 receptor-mediated effects in whole blood

G - Physics

01

N

G01N 33/567 (2006.01)

Patent

CA 2540260

Assay methods for analyzing whole blood to detect histamine H4 receptor- mediated effects, such as eosinophil shape change, cytoskeletal change, adhesion molecule up-regulation, or calcium flux are described. Such methods are useful in clinical and diagnostic applications.

L'invention concerne des procédés pour essais biologiques permettant d'analyser le sang total, ce qui permet de détecter les effets médiés par le récepteur H¿4?, tel que changement de forme éosinophile, le changement cytosquelettique, la régulation positive de molécules d'adhésion, ou un flux de calcium. Lesdits procédés sont utilisés dans des applications diagnostiques et cliniques.

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