Anaplastic lymphoma kinase modulators and methods of use

A - Human Necessities – 61 – K

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A61K 31/437 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2532800

The present invention comprises compounds and pharmaceutical compositions comprising the compounds that are inhibitors of ALK. The invention also comprises methods of using the compounds and compositions to treat diseases mediated by ALK, including diseases such as cancer, immunological disorders, cardiovascular diseases, and other degenerative disorders.

La présente invention concerne des composés et des compositions pharmaceutiques comprenant ces composés, qui sont des inhibiteurs de la protéine ALK. L'invention concerne également des méthodes d'utilisation de ces composés et de ces compositions pour le traitement de maladies induites par la protéine ALK, telles que le cancer, des troubles immunologiques, des maladies cardiovasculaires et d'autres affections dégénératives.

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