Anchored transferrin fusion protein libraries

Details Anchored transferrin fusion protein libraries Anchored transferrin fusion protein libraries

C - Chemistry, Metallurgy

07

K

C07K 14/00 (2006.01) C07H 17/00 (2006.01)

Patent

CA 2610931

Fusion proteins comprising a transferrin moiety, a stalk moiety, and cell wall linking member and peptide libraries thereof are disclosed. The present invention includes a method of screening peptide libraries displayed in fusion proteins expressed by host cells. The fusion proteins of the present invention include transferrin fusion proteins capable of expression in yeast.

Protéines de fusion comprenant une fraction transférine, une fraction tige et un élément de liaison à la paroi cellulaire, et librairies peptidiques correspondantes. Procédé d'analyse de librairies peptidiques présentées dans les protéines de fusion exprimées par des cellules hôtes. Les protéines de fusion considérées englobent les prptéines de fusion transférine capables d'expression dans la levure.

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