(-) and (+) 10-(1-azabicyclo[2.2.2.]oct-3-yl-methyl)-10...

Details (-) and (+) 10-(1-azabicyclo[2.2.2.]oct-3-yl-methyl)-10... (-) and (+) 10-(1-azabicyclo[2.2.2.]oct-3-yl-methyl)-10...

C - Chemistry, Metallurgy

07

D

C07D 453/02 (2006.01) A61K 31/54 (2006.01)

Patent

CA 2114844

2114844 9303029 PCTABS00019 The description refers to dextrorotatory (+) and levorotatory (-) enantiomorphs of quaternary ammonium derivatives of 10-(1-azabicyclo[2.2.2.]oct-3-yl-methyl)-10 H-phenothiazine as per general formula (I), where R = C1-4 alkyl, cyclopropyl, X = halogen, dimethyl sulphate, p-toluenesulphonic acid as well as to the preparation of same and to the pharmaceutical compositions containing them.

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