Androstenone derivative

C - Chemistry – Metallurgy – 07 – J

Patent

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Details

C07J 73/00 (2006.01) A61K 31/58 (2006.01) C07C 235/82 (2006.01) C07J 3/00 (2006.01) C07J 41/00 (2006.01)

Patent

CA 2170047

The present invention relates to the compound of formula (I), also known as 17.beta.-N-(2,5- bis(Trifluoromethyl))phenylcarbamoyl-4.-aza-5.alpha.-androst-1- en-3-one, solvates thereof, its preparation, intermediates used in its preparation, pharmaceutical formulations thereof and its use in the treatment of androgen responsive and mediated diseases.

La présente invention a pour objet le composé selon la formule (I), également connu sous le nom de 17 beta -N-(2,5-bis(trifluorométhyl))phénylcarbamoyl-4-aza-5 alpha -androst-1-en-3-one, des solvates de celui-ci, sa préparation, des intermédiaires utilisés pour celle-ci, des formulations pharmaceutiques de ce composé et son utilisation dans le traitement des maladies répondant aux androgènes ou à médiation par les androgènes.

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