Androstenones

Details Androstenones Androstenones

C - Chemistry, Metallurgy

07

J

C07J 41/00 (2006.01) A61K 31/58 (2006.01) C07C 235/82 (2006.01) C07J 3/00 (2006.01) C07J 73/00 (2006.01) C07J 75/00 (2006.01)

Patent

CA 2478971

The present invention relates to compounds of formulae (III) and (IV) Image wherein R2 is H or CH3, and R3 is Image wherein R6 is trifluoromethyl, phenyl optionally substituted with one or more halogens or branched (C4-7) alkyl groups, or branched (C4-7) alkyl; either of R7 or R8 is trifluoromethyl, halogen, phenyl optionally substituted with one or more halogens or branched (C4-7) alkyl groups, or branched (C4-7) alkyl, while the other is hydrogen or halogen; and X is hydrogen or halogen, or a solvate thereof and their use in the treatment of androgen responsive and mediated diseases.

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