Androstenones

C - Chemistry – Metallurgy – 07 – J

Patent

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Details

C07J 73/00 (2006.01) A61K 31/58 (2006.01) C07C 235/82 (2006.01) C07J 3/00 (2006.01) C07J 41/00 (2006.01) C07J 75/00 (2006.01)

Patent

CA 2449679

The present invention relates to compounds of formula (I), (see formula I) wherein carbons 1 and 2 are joined by either a single or a double bond; R1 is hydrogen or methyl; R2 is hydrogen or methyl; R3 is (A) (see formulas (A) and (B) wherein X, W, Z, R4, R5, R6, R7 and R8 are various groups, and pharmaceutically acceptable solvates thereof and their use in the treatment of androgen responsive and mediated diseases.

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