Anellated dihydropyridines and their use in the production...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 217/14 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 217/16 (2006.01) C07D 405/12 (2006.01) C07D 409/00 (2006.01) C07D 409/06 (2006.01) C07D 409/14 (2006.01) C07D 471/04 (2006.01) C07D 491/056 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2178088

A compound of the general formula (I) in which A is a benzo, indolo or thiene radical, R1 is thienyl or the group (a) in which R7, R8 and R9 may be mutually independently methyl, ethyl, propyl, phenyl or benzyl, where not more than 2 of the components may be phenyl or benzyl; R2, m, R3 and R4 are as defined in the description; and pharmaceutical preparations containing this compound and their novel pharmaceutical uses.

L'invention concerne un composé de la formule générale (I) où A représente un reste benzo, indolo ou thiéno; R?1¿ représente thiényle ou le groupe (a) où R?7¿, R?8¿ et R?9¿ peuvent indépendamment l'un de l'autre représenter méthyle, éthyle, propyle, phényle ou benzyle, et deux des substituants au plus pouvant être simultanément phényle ou benzyle; R?2¿, m, R?3¿ et R?4¿ sont définis dans la description. L'invention concerne par ailleurs des préparations pharmaceutiques contenant ces composés ainsi que leurs nouvelles applications pharmacologiques.

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