C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/17 (2006.01)
Patent
CA 2548208
The present invention relates to polynucleotides and proteins associated with vasculogenesis- and angiogenesis-related disorders. The invention further relates to methods for the identification of compounds that modulate the expression of angiogenesis-related genes and gene products and to using such compounds as therapeutic agents in the treatment of angiogenesis-related disorders. The invention also relates to methods for the diagnostic evaluation, genetic testing and prognosis of angiogenesis-related disorders, and to methods and compositions for the treatment these disorders.
L'invention concerne des polynucléotides et des protéines associés à des troubles relatifs à la vasculogénèse et l'angiogénèse. L'invention concerne également des procédés d'identification de composés modulant l'expression des gènes et des produits géniques relatifs à l'angiogénèse et l'utilisation de tels composés comme agents thérapeutiques dans le traitement de troubles relatifs à l'angiogénèse. L'invention concerne enfin des procédés d'évaluation de diagnostic, de test génétique et de pronostic de troubles relatifs à l'angiogénèse, ainsi que des procédés et des compositions destinés au traitement de ces troubles.
Hellstrom Mats
Kalen Mattias
Wallgard Elisabet
Angiogenetics Sweden Ab
Bioinvent International Ab
Gowling Lafleur Henderson Llp
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