Angiogenesis inhibitor and novel compound

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 307/36 (2006.01) A61K 31/05 (2006.01) A61K 31/085 (2006.01) A61K 31/09 (2006.01) A61K 31/335 (2006.01) A61K 31/341 (2006.01) C07D 307/68 (2006.01) C07D 407/04 (2006.01)

Patent

CA 2153686

An angiogenesis inhibitor comprising, as an active agent, Compound (I) represented by the formula below: Image (I) where R1 is a lower alkyl group, an alkoxycarbonyl group or a carboxyl group; and R2, R3 and R4 may be the same or different and represent a hydrogen atom, a hydroxyl group, a methoxy group or an acetoxy group. This compound has a remarkable angiogenesis inhibition activity, and an angiogenesis inhibitor useful for treatment of various diseases are provided.

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