Angiogenesis inhibitors and activators from shark cartilage

A - Human Necessities – 61 – K

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A61K 35/32 (2006.01) A61K 35/60 (2006.01)

Patent

CA 2288269

A process for obtaining an angiogenesis inhibitor and an angiogenesis activator from shark cartilage comprising, as the key step, the aqueous extraction of dried shark cartilage. The angiogenesis inhibitor obtained is more potent than shark cartilage not subjected to the extraction step. The angiogenesis inhibitor is particularly useful for the prevention or treatment of cancer. The angiogenesis activator is particularly useful for stimulating wound healing.

La présente invention concerne un procédé d'obtention d'un inhibiteur de l'angiogenèse et d'un activateur de l'angiogenèse. Ce procédé consiste essentiellement en une extraction aqueuse de cartilage de requin séché. L'inhibiteur d'angiogenèse ainsi obtenu est plus puissant que le cartilage de requin n'ayant pas subi l'opération d'extraction. Cet inhibiteur d'angiogenèse convient particulièrement pour la prévention ou le traitement du cancer. L'activateur d'angiogénèse convient particulièrement pour stimuler la guérison des blessures.

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