Angiogenesis inhibitory antibodies

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/18 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 51/10 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12N 9/10 (2006.01) C12N 11/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2148244

2148244 9410331 PCTABS00032 Antibodies, including monoclonal antibodies, specific for proliferating/angiogenic human endothelial cells such as human umbilical vein endothelial cells and human umbilical artery endothelial cells, and conjugates of these antibodies with a toxin material or label, are useful for inhibition of angiogenesis or for treatment of angiogenesis-dependent disease.

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