Angiogenesis promoters and angiogenesis potentiators

Details Angiogenesis promoters and angiogenesis potentiators Angiogenesis promoters and angiogenesis potentiators

A - Human Necessities

61

K

A61K 31/501 (2006.01)

Patent

CA 2301852

An angiogenesis promoter and angiogenesis potentiator containing a pyridazinone compound of the formula (I) (see formula I) wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof, as an active ingredient. The pyridazinone compound (I) and a pharmacologically acceptable salt thereof in the present invention promote angiogenesis and potentiate the angiogenic effect of a drug having such effect, and are useful as an angiogenesis promoter and angiogenesis potentiator.

Agents promoteurs et agents potentialisateurs de la néovascularisation contenant en tant qu'ingrédient actif des composés de pyridazinone représenté par la formule (I), ou leurs sels acceptables sur le plan pharmacologique dans laquelle chaque symbole est conforme à sa définition mentionnée dans le descriptif. Ces composés de pyridazinone selon la formule (I), ainsi que leurs sels acceptables sur le plan pharmacologique, exercent des effets de promotion de la néovascularisation et potentialisent les médicaments exerçant de tels effets, ce qui les rend utiles en tant qu'agents promoteurs et qu'agents potentialisateurs de la néovascularisation.

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