Angiogenic material and uses thereof

Details Angiogenic material and uses thereof Angiogenic material and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 11/08 (2006.01) A61K 9/50 (2006.01) A61K 35/12 (2006.01) B01J 13/02 (2006.01)

Patent

CA 2161863

An angiogenic material is disclosed which promotes extensive vascularization when implanted in animal tissue. The angiogenic material is preferably used in microcapsule coatings and microspheres for implantation in animals. In microcapsules, the angiogenic material promotes better exchange of nutrients, waste products and cellular products between encapsulated cells and the circulatory system of the host animal. Microspheres containing the angiogenic material may be used to assist in recovery of ischemic heart muscle by injection of the microspheres into the heart muscle or blood vessels serving the ischemic area. Also disclosed is a method of forming small microcapsules and microspheres by passing cell aggregates or air bubbles through layers of a density gradient.

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