Angiopoietin-2 specific binding agents

Details Angiopoietin-2 specific binding agents Angiopoietin-2 specific binding agents

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/385 (2006.01) A61K 39/395 (2006.01) A61P 9/00 (2006.01) A61P 35/00 (2006.01) C07K 16/22 (2006.01) C07K 16/46 (2006.01) C12N 5/16 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01) G01N 33/53 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2583910

Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies.

L'invention concerne des agents de liaison spécifiques, tels que des anticorps entièrement humains qui se lient à l'angiopoïétine-2. Cette invention a aussi trait à des fragments à chaîne lourde, à des fragments à chaîne légère et à des régions déterminant la complémentarité (CDR) des anticorps, ainsi qu'à des méthodes d'élaboration et d'utilisation desdits anticorps.

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