Angiopoietin-2 specific binding agents

Details Angiopoietin-2 specific binding agents Angiopoietin-2 specific binding agents

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/18 (2006.01) C07K 16/22 (2006.01) C12N 5/12 (2006.01) C12P 21/08 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2461435

Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies.

Cette invention a trait à des agents de liaison spécifiques, tels que des anticorps totalement humains, se fixant à l'angiopoïétine-2. Elle concerne également des fragments de chaîne lourde, des fragments de chaîne légère ainsi que des régions complémentaires de détermination (CDR) de ces anticorps et des méthodes de production et d'utilisation de ces anticorps.

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