Angiopoietin-related protein and nucleic acids

Details Angiopoietin-related protein and nucleic acids Angiopoietin-related protein and nucleic acids

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/515 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2362547

The present invention provides for an isolated nucleic acid molecule encoding AR-2. The invention further provides isolated AR-2 protein substantially free of other proteins. The invention further provides a host-vector system for the production of AR-2 and a method of producing AR-2. The invention also provides an antibody which specifically binds AR-2 and a composition comprising AR-2.

La présente invention se rapporte à une molécule d'acide nucléique isolé codant pour le facteur associé à l'angiopoïétine (AR-2). Elle se rapporte aussi à une protéine de AR-2 isolée et sensiblement non associée à d'autres protéines. Elle se rapporte également à un système de vecteur-hôte pour la production de AR-2 et à une méthode de production de AR-2. L'invention se rapporte en outre à un anticorps qui se lie spécifiquement à AR-2 et à une composition contenant AR-2.

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