Angiostatic compositions comprising truncated tyrosyl-trna...

A - Human Necessities – 61 – K

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A61K 38/53 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 27/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2718153

Angiostatic compositions are provided comprising truncated forms of tyrosyl tRNA synthetase polypeptides. Also provided are methods of using such compositions in the treatment of conditions that benefit from decreased angiogenesis and/or neovascularization.

L'invention concerne des compositions angiostatiques comportant des formes tronquées de polypeptides de tyrosyle ARN de transfert synthétase. Des procédés d'utilisation de telles compositions dans le traitement d'états qui bénéficient d'une angiogenèse et/ou d'une néovascularisation diminuée sont également décrits.

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