C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/48 (2006.01) A61K 38/16 (2006.01) A61K 38/48 (2006.01) A61P 9/00 (2006.01) A61P 9/02 (2006.01) C12P 21/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2344274
The present invention relates to the discovery of novel genes encoding an angiotensin converting enzyme; Angiotensin Converting Enzyme-2 (ACE-2). The invention provides therapeutics, prognostic and diagnostics methods for treating blood pressure related disorders as well as various types of allergic conditions, among others. Also disclosed are screening assays for identifying compounds for treating and preventing these conditions.
La présente invention concerne la découverte de nouveaux gènes codant une enzyme de conversion d'angiotensine appelée ACE-2. L'invention concerne des agents thérapeutiques, des procédés de pronostic et diagnostic permettant de traiter les troubles liés à la pression sanguine ainsi que divers types de conditions allergiques, entre autres. Des dosages de criblage permettant d'identifier des composés permettant de traiter et de prévenir ces états sont également décrits.
Acton Laurene Susan
Hsieh Frank Y.
Robison Keith Earl
Borden Ladner Gervais Llp
Millennium Pharmaceuticals Inc.
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