Angiotensin-converting enzyme inhibitors

Details Angiotensin-converting enzyme inhibitors Angiotensin-converting enzyme inhibitors

C - Chemistry, Metallurgy

07

D

260/271, 195/122

C07D 471/04 (2006.01) C07D 455/02 (2006.01) C12N 1/20 (2006.01) C12P 17/18 (2006.01)

Patent

CA 1204684

X-5950 ABSTRACT Angiotensin I converting enzyme inhibitors A-58365 factors A, B, and C are produced by culturing Streptomyces chromofuscus NRRL 15098 under submerged aerobic fermentation conditions and are isolated and purified from the acidic filtered fermentation broth via chromatography, in particular HPLC. The factors are useful hypotensive agents.

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