Angiotensin i-converting enzyme inhibitory substance

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 21/00 (2006.01) A23L 1/305 (2006.01) A61K 38/56 (2006.01) C07K 4/08 (2006.01) C12N 9/50 (2006.01)

Patent

CA 2360015

The subject of the invention is to produce a peptide with potent the angiotensin I-converting enzyme (ACE) inhibitory activity by decomposing the protein contained in wakame with protease, using wakame being a food material ingested daily as a raw material, and to provide a safe food composition with hypotensive activity, using the treatment product thereof as a raw material. The inventors have found that, when performing the decomposing treatment of wakame with various proteases, a group of endo-type enzymes produced by Bacillus produce peptides with particularly strong ACE inhibitory activity, leading to the completion of the invention.

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