Angiotensin ii receptor antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/12 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) C07D 213/80 (2006.01) C07D 239/42 (2006.01) C07D 257/04 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2050723

-159- ABSTRACT OF THE DISCLOSURE Novel pyrimidine, pyridine, pyridazine, pyrazine and triazine compounds are provided of the formula (I). (I) Image The compounds of the invention are useful for treating hypertension, edema, renal failure, congestive heart failure, psoriasis and glaucoma, and in the prevention and treatment of atherosclerosis or to treat gastrointestinal disorders associated with enhanced contractility and/or motility of intestinal smooth muscle or to treat contractile disorders of the uterus.

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