Anhydro-vinca derivatives

Details Anhydro-vinca derivatives Anhydro-vinca derivatives

C - Chemistry, Metallurgy

07

D

260/237.3

C07D 519/04 (2006.01)

Patent

CA 1057750

ABSTRACT OF THE DISCLOSURE The present invention relates to novel dimeric vinca alkaloid anhydro derivatives and to a process for preparing said anhydro derivatives which comprises con- tacting the dimeric vinca alkaloid with cold concentrated sulfuric acid. The anhydro derivatives are useful as mitotic inhibitors or as intermediates for the preparation of other oncogenetically active alkaloids.

253622

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