C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/496 (2006.01) A61P 31/00 (2006.01) C07D 215/56 (2006.01)
Patent
CA 2481308
The present invention relates to the novel anhydrous crystalline forms I and II of 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl) 4-oxo-l, 4- dihydroquinoline-3-carboxylic acid (gatifloxacin) which can be depicted as Formula (I). The present invention also relates to methods of making the anhydrous Forms I and II of Gatifloxacin, use of the forms and methods for preparing them.
L'invention concerne de nouvelles formes cristallines anhydres I et II de l'acide 1-cyclopropyl-6-fluoro-8-méthoxy-7-(3-méthyl-1-pipérazinyl) 4-oxo-l, 4-dihydroquinoléine-3-carboxylique (gatifloxacine) qui peut être représenté par la formule (1). L'invention concerne également des procédé de fabrication des formes anhydres I et II de gatifloxacine, l'utilisation de ces formes, ainsi que leurs procédés de préparation.
Kumar Rapolu Rajesh
Raju Chakilam Naga
Raju Vetukuri Venkata Naga Kali Vara Prasada
Reddy Manne Satyanarayana
Reddy Ningam Srinivas
Dr. Reddy's Laboratories Limited
Marks & Clerk
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