C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 519/04 (2006.01) A61K 31/475 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2677269
The present invention relates to anhydrous crystalline vinflunine salts obtained with 1 or 2 equivalents of a pharmaceutically acceptable mineral or organic acid [Acid] 1 or 2 in which [Acid] represents hydrobromic, sulfuric, lactic and fumaric acids for the group of water-soluble crystalline salts, and para-toluene sulfonic, benzoic, mandelic and para- hydroxy benzoic acids for the group of relatively insoluble crystalline salts.
L'invention concerne des sels de vinflunine anhydres cristallins que l'on obtient avec 1 ou 2 équivalents d'un acide minéral ou organique pharmaceutiquement acceptable.
Maurel Jean-Louis
Pena Richard
Ribet Jean-Paul
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Pierre Fabre Medicament
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