Anhydrovinblastine for the treatment of cancer

Details Anhydrovinblastine for the treatment of cancer Anhydrovinblastine for the treatment of cancer

A - Human Necessities

61

K

A61K 31/475 (2006.01)

Patent

CA 2199065

The present invention is particularly directed to the use of a derivative of vinblastine, 3',4'-anhydrovinblastine (AHVB), which differs from vinblastine in that it possesses a double bond at the 3',4' position of the caranthine nucleus rather than the hydroxyl group that is present in the parent structure, as an anti-neoplastic agent in the therapeutic treatment of cancer.

La présente invention a trait particulièrement à l'utilisation d'un dérivé de la vinblastine, la 3',4'-anhydro-vinblastine (AHVB), qui diffère de la vinblastine en ce qu'elle présente une double liaison en position 3',4' du noyau catharantine plutôt qu'au groupe hydroxyle qui est présent dans la structure fondamentale, en tant qu'agent antinéoplastique dans le traitement du cancer.

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