Anilide derivative

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 323/41 (2006.01) C07C 317/28 (2006.01) C07C 317/44 (2006.01) C07C 323/60 (2006.01) C07C 327/30 (2006.01) C07C 327/32 (2006.01)

Patent

CA 2096970

An anilide derivative useful as an atherosclerosis treating drug, represented by the following formula (I): Image wherein X is an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to 4 carbon atoms; Y is a hydrogen atom or an alkoxy group having 1 to 4 carbon atoms; Z is an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to 4 carbon atoms; A is an alkylene group having 1 to 4 carbon atoms; R is an alkyl group having 6 to 20 carbon atoms, an alkanoyl group having 2 to 20 carbon atoms or a benzyl group which may be substituted with an alkyl group having 1 to 4 carbon atoms; and n is 0, 1 or 2.

Dérivé anilide utile comme médicament pour le traitement de l'athérosclérose, représenté par la formule I suivante : Image où X est un groupe alkyle ayant de 1 à 4 atomes de carbone ou un groupe alkoxy ayant 1 à 4 atomes de carbone, Y est un atome d'hydrogène ou un groupe alkoxy ayant de 1 à 4 atomes de carbone, Z est un groupe alkyle ayant de 1 à 4 atomes de carbone ou un groupe alkoxy ayant de 1 à 4 atomes de carbone, A est un groupe alkylène ayant de 1 à 4 atomes de carbone, R est un groupe alkyle ayant de 6 à 20 atomes de carbone, un groupe alkanoyle ayant de 2 à 20 atomes de carbone ou un groupe benzyle qui peut être substitué par un groupe alkyle ayant de 1 à 4 atomes de carbone, et n est égal à 0, 1 ou 2.

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