Anilides and analogs as rho kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/12 (2006.01) A61K 31/415 (2006.01) A61K 31/4725 (2006.01) C07D 213/40 (2006.01) C07D 231/12 (2006.01) C07D 239/42 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2709879

Compounds useful as Rho kinase inhibitors of formula (I): wherein variable are as defined herein are provided. Methods of treatment of malconditions mediated by Rho kinase, and methods of preparation of the compounds, are also provided.

L'invention concerne des composés qui conviennent comme inhibiteurs de la Rho kinase, représentés par la formule (I) dans laquelle les variables sont telles que définies dans la description. L'invention concerne aussi des procédés de traitement d'états pathologiques induits par la Rho kinase et, des procédés de préparation de ces composés.

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