C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/313, 260/278
C07D 249/04 (2006.01) C07D 403/06 (2006.01) C07D 413/06 (2006.01)
Patent
CA 1173035
ABSTRACT The invention relates to new anilino-1,2,3 triazole derivatives of general formula (I) Image wherein R1 represents an alkyl group with 1 to 4 carbon atoms, R2 represents a hydrogen atom, a halogen atom, an amino group, a nitro group, an alkoxy group with 1 to 3 carbon atoms, an ester group COOR6 or a methyl group in the 3- or 4- position, R3 represents a hydrogen atom or a halogen atom in the 5- position, R4 and R5 represent alkyl groups with 1 to 4 carbon atoms, or together with the nitrogen atom, represent a piperidine, pyrrolidine or morpholine ring, R6 represents an alkyl group with 1 to 3 carbon atoms, and n represents the number 2 or 3, and the acid addition salts thereof. The new compounds may be prepared by reacting a triazole derivative of general formula Image (III) wherein R1 to R3 are as hereinbefore defined, with a compound of general formula Image (IV) wherein R4, R5 and n are as hereinbefore defined and X represents a halogen, and they may be used as pharmaceuticals for the treatment of blood flow disorders and sleep disorders.
410567
Koppe Herbert
Kuhn Franz J.
Kummer Werner
Reichl Richard
Stahle Helmut
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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