C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/42 (2006.01) A61K 31/505 (2006.01) A61P 29/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2431160
Compounds having activity as inhibitors of IKK are disclosed, particularly IKK- 2. The compounds of this invention are anilinopyrimidine derivatives having the following structure: (A) wherein R1 and R6 are as defined herein. Such compounds have utility in the treatment of a wide range of conditions that are responsive to IKK inhibition. Thus, methods or treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.
La présente invention concerne des composés qui possèdent une activité inhibitrice de IKK, en particulier de IKK-2. Ces composés sont des dérivés d'anilinopyrimidine représentés par la structure suivante: (A). Dans cette structure les R¿1?, ,R¿6? sont tels que définis dans les spécifications. Ces composés conviennent pour le traitement d'une grande plage de pathologies sensibles à l'inhibition des IKK. Cette invention concerne aussi des techniques de traitement de ces pathologies, de même que des compositions pharmaceutiques contenant un ou plusieurs composés parmi ceux qui sont présentés dans cette invention.
Bhagwat Shripad S.
Erdman Paul E.
Kois Adam
Macfarlane Karen J.
Palanki Moorthy S. S.
Osler Hoskin & Harcourt Llp
Signal Pharmaceuticals Inc.
Signal Pharmaceuticals Llc
LandOfFree
Anilinopyrimidine derivatives as ikk inhibitors and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anilinopyrimidine derivatives as ikk inhibitors and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anilinopyrimidine derivatives as ikk inhibitors and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1688927