G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/48 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01) G01N 33/564 (2006.01)
Patent
CA 2118457
ABSTRACT OF THE DISCLOSURE Disclosed is an animal model which is constructed by transplanting IgE-producing vegetative cells in a non-rejecting animal to endow the animal with ability to induce IgE-mediated allergic reaction caused by the transplanted cells, a method of preparing the animal model and a method of screening prophylactic and therapeutic agents for IgE-related diseases. Screening of the prophylactic and therapeutic agents for IgE- related diseases can be efficiently and expediently carried out using the animal model according to the present invention in which IgE-mediated allergic reaction is repeatedly induced by repeated antigen challenge.
Hirama Minoru
Naito Koji
Okumura Ko
Ra Chisei
Ra Chisei
Riches Mckenzie & Herbert Llp
Yoshitomi Pharmaceutical Industries Ltd.
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