C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 21/02 (2006.01) A61K 8/66 (2006.01) A61K 38/16 (2006.01) A61K 38/48 (2006.01) C12N 1/20 (2006.01) C12N 9/52 (2006.01)
Patent
CA 2540072
Media and processes for the fermentation of Clostridium botulinum and obtaining a botulinum toxin for use in formulating botulinum toxin pharmaceutical compositions. The growth media can contain significantly reduced levels of meat or dairy by-products using non-animal based products to replace the animal-derived products. Preferably, the media used are substantially free of animal derived products.
L'invention concerne des milieux ainsi que des procédés de fermentation de Clostridium botulinum et de production d'une toxine botulinique à utiliser dans des compositions pharmaceutiques renfermant une toxine botulinique. Ces milieux de culture peuvent contenir des taux sensiblement réduits de sous-produits carnés ou laitiers grâce à l'utilisation de produits d'origine non animale en remplacement des produits d'origine animale. Les milieux utilisés sont de préférence exempts de produits d'origine animale.
Donovan Stephen
Allergan Inc.
Gowling Lafleur Henderson Llp
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