Animal protein-free media for cultivation of cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/02 (2006.01) C12N 1/16 (2006.01) C12N 1/20 (2006.01) C12N 7/02 (2006.01)

Patent

CA 2585518

The present invention relates to animal protein-free cell culture media comprising polyamines and a plant- and/or yeast-derived hydrolysate. The invention also relates to animal protein-free culturing processes, wherein cells can be cultivated, propagated and passaged without adding supplementary animal proteins in the culture medium. These processes are useful in cultivating cells, such as recombinant cells or cells infected with a virus, and for producing biological products by cell culture processes.

L'invention concerne des milieux de culture de cellules exempts de protéine animale, comprenant des polyamines et un hydrolysat dérivé d'une plante et/ou de levure. L'invention concerne en outre des procédés de culture exempts de protéine animale, procédés dans lesquels les cellules peuvent être cultivées, propagées et subir des passages, sans addition de protéines aminales au milieu de culture. Ces procédés sont utilisé en culture des cellules, par exemple de cellules recombinantes ou de cellules infectées par un virus, et pour la production de produits biologiques par des processus de culture de cellules.

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