Animal protein free media for cultivation of cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/00 (2006.01) C12N 5/07 (2010.01) A61K 39/12 (2006.01) A61K 39/125 (2006.01) A61K 39/145 (2006.01) A61K 39/215 (2006.01) A61K 39/275 (2006.01) A61K 39/285 (2006.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2491992

The present invention relates to animal protein free cell culture media comprising a combination of non-animal derived peptides derived from soy hydrolysate and yeast hydrolysate. The invention also provides an animal protein free culture process, wherein cells are cultivated, propagated and passaged without animal-derived components. This process is useful for cultivating cells, such as recombinant cells or cells infected with a virus, and for production of biological products by cell culture processes under conditions devoid of animal protein components.

L'invention concerne un milieu de culture de cellules exempt de protéines animales, qui comprend une combinaison de peptides d'origine non animale obtenus à partir d'hydrolysat de soja et d'hydrolysat de levure. L'invention concerne aussi un procédé de culture exempt de protéines animales, dans lequel des cellules sont mises en culture, propagées et soumises à des passages sans utiliser de composants d'origine animale. Le procédé sert à cultiver des cellules telles que des cellules recombinées ou des cellules infectées par un virus, et pour la production de produits biologiques par des procédés de culture cellulaire, dans des conditions excluant l'utilisation de composants protéiniques d'origine animale.

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