Animals with targeted gene deletion

Details Animals with targeted gene deletion Animals with targeted gene deletion

A - Human Necessities

01

K

A01K 67/027 (2006.01) A61K 38/45 (2006.01) C12N 5/10 (2006.01) C12Q 1/00 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/564 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2234708

A non-human animal carrying a disruption of a gene encoding a lyn protein tyrosine kinase provides a convenient system for the study of diseases associated with or caused by lyn deficiency, and for the testing of therapeutic agents for the treatment or prevention of diseases which include autoimmune diseases, allergy, asthma and malignant disease.

Un animal porteur d'une disruption d'un gène codant une protéine tyrosine kinase de lyn constitue un système commode pour l'étude de maladies associées à la déficience du lyn ou causées par elle ainsi que pour l'expérimentation d'agents thérapeutiques destinés au traitement ou à la prévention de maladies comprenant les maladies auto-immunes, l'allergie, l'asthme et les affections malignes.

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