Anionic ion exchange resins with cholesterol decreasing...

C - Chemistry – Metallurgy – 08 – F

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402/182, 402/274

C08F 8/32 (2006.01) A61K 31/74 (2006.01) C08F 8/44 (2006.01) C08F 212/00 (2006.01) C08F 220/46 (2006.01) C08G 65/32 (2006.01) C08G 65/333 (2006.01)

Patent

CA 1141892

ABSTRACT These resins are in particular non toxic styrene, acrylic or epoxy resins, with strong cholesterol-decreasing properties which have an apparent density in water of 0.18 to 0.20 g of dry material/ml and water absorption capacity of 69 to 73% by weight of the po lymer weight. The process for producing anionic ion exchange resins with strong cholesterol-decreasing properties in which a mixture of monomers containing a critical percentage of cross-linking monomer, consists of polymerising at a low rate so as to give the polymer a criti- cally predetermined and uniformly distributed degree of cross- linkage, corresponding to an apparent density in water of 0.18 to 0.20 of dry material/ml with water absorption capacity of 69 to 73% by weight of the polymer weight, wherein the polymerisat- ion catalyst used in an organic peroxide in a concentration of 0.2 to 3%, and the cross-linking agent used is a divinyl compound in a percentage of 1.5 to 12%, at a polymerisation temperature of 50° to 80°C.

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