Anisole bromination

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

260/645.9

C07C 41/22 (2006.01) C07C 43/225 (2006.01)

Patent

CA 2023977

Abstract An improved method for the production of 4-bromo-3- alkylanisole, particularly 4-bromo-3-methylanisole is described. The method involves establishing 3-alkylanisole as a vapor in a reaction zone of a reactor, and establishing bromine as a vapor. Thereafter the bromine vapor is introduced to the reaction zone of the reactor and commingled with the established 3-alkylanisole vapor. Dibrominated impurity is substantially reduced. 6405 Page

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