Anisole derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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260/351, 260/306

C07D 317/48 (2006.01) C07D 317/64 (2006.01) C07D 405/06 (2006.01) C07D 491/04 (2006.01)

Patent

CA 1285571

ABSTRACT: ANISOLE DERIVATIVES There is provided a novel anisole derivative represented by the following formula (I): (I) Image wherein A to D are defined as follows: (1) when A, B and C are each a hydrogen atom, D represents -OH, a halogen atom, -CO2R1 of which R1 represents a lower alkyl group, -SO2R2 of which R2 represents a lower alkyl group, or Image ; (2) when A and C are each a hydrogen atom and B is -OH, D represents -CO2R3 of which R3 represents a lower alkyl group; (3) when A is a hydrogen atom and B and C form an oxo group =O together, D reprcsents -CO2R4 of which R4 represents a lower alkyl group; and (4) when B and C are each a hydrogen atom and D is a halogen atom, A represents -CHO. The anisole derivative of the present invention can be used as an intermediate for the synthesis of cotarnine.

517606

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