C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) A61K 39/395 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2619052
The present invention encompasses isolated antibodies, or antigen-binding portions thereof, that specifically bind to the p19 subunit of IL-23. These antibodies, or antigen-binding portions thereof, are high affinity, neutralizing antibodies useful for the treatment of autoimmune disease.
La présente invention concerne des anticorps isolés ou des fractions de liaison à l'antigène de ceux-ci qui se lient spécifiquement à la sous-unité p19 de l'IL-23. Ces anticorps, ou fractions de liaison à l'antigène de ceux-ci, constituent des anticorps neutralisants à haute affinité utiles dans le traitement d'une maladie auto-immune.
Beidler Catherine Brautigam
Bright Stuart Willis
Dickinson Craig Duane
Kikly Kristine Kay
Marquis David Matthew
Eli Lily And Company
Gowling Lafleur Henderson Llp
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