Annelated indolo (3,2-c)-lactams

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 471/06 (2006.01) C07D 471/16 (2006.01) C07D 487/06 (2006.01) C07D 487/16 (2006.01) C07D 513/06 (2006.01) C07D 513/16 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2005974

DIR 0427 Abstract The invention relates to a group of new annelated indolo [3,2-c] lactam derivatives of the formula Image having an antagonistic activity on 5-HT receptors. The compounds can be used for the treatment of symptoms which are caused by excessive stimulation of said receptors in the gastrointestinal system, the central nervous system, the cardiovascular system, the respiratory system, and for alleviating or preventing withdrawal symptoms which are induced by abuse of drugs.

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