Annulated 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines

C - Chemistry – Metallurgy – 07 – D

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C07D 221/06 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07D 215/42 (2006.01) C07D 221/16 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 475/00 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01) C07D 513/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2282112

Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans. 23

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