Antagonistic angiotension ii analogues containing an...

C - Chemistry – Metallurgy – 07 – K

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530/7.14

C07K 7/14 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1108124

ABSTRACT OF THE DISCLOSURE There are disclosed now angiotensin II analogues of the general formula I Image (I) wherein X is a radical derived from an aliphatic .alpha.-aminooxy carboxylic acid and Y stands for a radical derived from an aliphatic .alpha.-amino-carboxylic acid, and acid addition salts and complexes thereof. The new compounds possess antagonistic properties and find their application in the diagnosis and treatment of hypertensions depending on renin.

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