Antagonistic anti-avb3 integrin antibodies

Details Antagonistic anti-avb3 integrin antibodies Antagonistic anti-avb3 integrin antibodies

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 51/10 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2284726

Monoclonal antibodies that recognize the .alpha.v.beta.3 integrin receptor complex, but do not significantly bind to .alpha.IIb.beta.IIIa, inhibit .alpha.v.beta.3 integrin-mediated diseases.

L'invention concerne des anticorps monoclonaux reconnaissant le complexe récepteur de l'intégrine .alpha.¿v?.beta.¿3?, mais ne se liant pas de manière significative à .alpha.¿IIb?.beta.¿IIIa?, qui ont une action inhibitrice sur les maladies dont la médiation est assurée par l'intégrine .alpha.¿v?.beta.¿3?.

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