Antagonists of alpha-melanocyte stimulating hormone and...

Details Antagonists of alpha-melanocyte stimulating hormone and... Antagonists of alpha-melanocyte stimulating hormone and...

C - Chemistry, Metallurgy

07

K

C07K 5/097 (2006.01) A61K 38/06 (2006.01) C07K 5/087 (2006.01) C07K 14/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2210737

Peptide antagonists of .alpha.-melanocyte stimulating hormone are disclosed, together with methods of inhibiting the effects of .alpha.-melanocyte stimulating hormone or cells or tissues sensitive to that hormone. In particular, methods for lightening the pigmentation of skin and for treating malignant melanoma, as well as kits for practicing the invention are also disclosed.

L'invention concerne des antagonistes peptidiques de l'hormone de stimulation d'.alpha.-mélanocytes, ainsi que des procédés d'inhibition des effets de l'hormone de stimulation d'.alpha.-mélanocytes sur des cellules ou des tissus sensibles à cette hormone. En particulier, des procédés permettant d'éclaircir la pigmentation de la peau et de traiter des mélanomes malins, ainsi que des kits de mise en oeuvre de l'invention sont également décrits.

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